Superpower vs Function Health: Price, Tests, Folate and B12, Compared

Superpower and Function Health are both yearly blood-testing memberships with two draws a year, an app, and clinician involvement. As of October 2026, Superpower lists $349 per year for 150+ biomarkers and Function lists $365 per year for 160+ tests.¹² The biggest difference for our readers: Superpower lists folate and vitamin B12 in its baseline panel, while Function's included list did not name them.³⁴ This page compares verified facts from each company's own pages (checked October 2, 2026), then gives criteria for choosing. We have not used either service.

Side-by-side: verified facts

Prices, state lists, and panels change. Confirm on each company's site before you buy.

What the two have in common

The similarities are bigger than the marketing suggests. Both are cash-pay memberships that do not take insurance but say they are HSA/FSA eligible.⁵⁶ Both use two blood draws a year, both use Quest locations for in-person draws, and both offer at-home draws.⁵¹ Both sell add-on tests such as the Galleri multi-cancer test, and both describe their large panels as screening for early signs of more than 1,000 conditions; that is each company's claim, not an independent finding.⁸¹⁵ And both say they are meant to work alongside your regular doctor rather than replace one.⁵⁶

Two differences stand out beyond price. Function offers an MTHFR gene add-on; if you consider it, the CDC says people with common MTHFR variants can process folic acid and should not avoid it on that basis (see folic acid and MTHFR).⁴⁹ Superpower runs a marketplace that sells supplements and prescriptions, including compounded products it notes are not FDA-approved.⁶

For the full picture of each, read our Function Health review and Superpower Health review.

How to choose: the criteria that matter

Rather than naming a winner (we have not used either), here are the questions that separate them.

1. Do you need folate and B12 specifically? Superpower's published baseline includes both; Function's did not.³⁴
2. Where do you live? Each has a different list of states where it is not available.⁶⁵
3. How fast do you want results? Function says first results usually arrive within 48 hours; Superpower says about a week.⁵⁶
4. How much do you want bundled extras? Superpower leans on AI chat, health scores, and a marketplace; Function adds imaging at member pricing.¹⁵
5. Who will interpret your results? Both say clinicians are involved, but neither replaces a regular clinician who knows your history.⁵⁶

Choose Superpower if

• You want folate, RBC folate, vitamin B12, and MMA in the base price.³
• You live in one of the states Superpower lists as available.⁶
• You like an app-first experience with AI chat and a care team.¹
• A slightly lower listed annual price matters to you.¹

Choose Function Health if

• You want the larger listed test count (160+) and fast first results.⁵
• You live in a state Superpower does not cover, such as Alaska, Arkansas, Louisiana, or Mississippi (Function excludes only Rhode Island, Hawaii, and Puerto Rico).⁵⁶
• You are interested in add-on imaging at member pricing.⁵
• You are fine ordering folate and B12 separately, or you do not need them.⁴

Folate and B12: reading the results either service gives you

If you get folate and B12 results from any service:

• Serum folate reflects recent intake, and RBC folate reflects longer-term status.¹⁰¹¹
• A high folate result often reflects recent supplements or fortified foods and is not a diagnosis by itself.¹²¹¹
• Low or borderline results need a clinician to look at B12 and a blood count together, since the two deficiencies overlap.¹³¹⁴

Our folate blood test guide and folic acid and B12 page explain this in more depth.

A note on SiPhox vs Function Health

SiPhox Health works differently from both. Instead of a lab visit, it mails an at-home kit that collects blood from the upper arm, with results in 7 to 10 days, and you choose to test monthly, quarterly, or every 6 months.¹⁵ SiPhox lists its membership at $99 as an introductory offer, plus shipping.¹⁵ Its standard Longevity Essentials panel has 31 biomarkers and does not list folate or B12; its Ultimate 360 upgrade has 62 biomarkers, including folate and vitamin B12, listed at $224.¹⁶¹⁷ Choose SiPhox over Function if you want frequent at-home testing without a lab visit; choose Function if you want the larger once-or-twice-a-year panel drawn at a lab. Full details are in our SiPhox Health review.

Before you buy either

A Cochrane review of randomized trials in about 252,000 adults found general health checks had little or no effect on deaths from any cause or from cancer, and noted that screening can lead to extra tests and treatments.¹⁸ MedlinePlus notes that healthy people often have some results outside a reference range, and that you should use the same lab when tracking trends.¹⁹ That last point matters if you switch between services. For single tests instead of a membership, see our at-home blood test guide.

This article is for general education and is not medical advice. Doses and needs differ from person to person, so talk with your clinician or pharmacist about your situation. Read our editorial policy and medical disclaimer.