Superpower Health Review: Price, Biomarkers, Folate and B12, and What to Know

Superpower is a yearly blood-testing membership. As of October 2026 it lists a price of $349 per year, and it says that covers 150+ biomarkers across two blood draws (a baseline and a retest), plus an app, AI chat, and an on-demand care team.¹² This researched overview covers how it works, what it tests (folate and vitamin B12 are on its baseline list), where it is available, what it costs, and what to weigh before signing up. We have not used Superpower; product facts come from Superpower's own pages, checked on October 2, 2026.

Quick answer: who Superpower suits, and who should skip it

Superpower may suit an adult who wants a broad baseline panel that includes folate and B12, prefers an app with AI and care-team chat, lives in a covered state, and plans to share results with a regular clinician. Superpower says its membership is designed to complement a primary care doctor, not replace one, and is not for emergencies.²

It may not suit you if:

• You live in an excluded state. Superpower's FAQ lists nine states where it is not yet available.²
• You want the option of a refund. Superpower says it does not offer refunds at this time.²
• You have new symptoms. A wellness panel is not a substitute for a visit; lab results need your history and exam to make sense.³
• You only need one or two markers. A single test may cost less; see our at-home blood test guide.

What Superpower is and how it works

Superpower describes four steps:¹

1. Build your baseline. Your first draw is a broad baseline panel. Superpower says each draw is a quick lab visit, at 2,000+ Quest locations or at home.¹ At-home draws cost extra and are available in most major U.S. metros, according to Superpower.¹
2. See what matters. Results land in a dashboard with a biological age and 17 health scores.¹
3. Build your protocol. Superpower AI and the care team suggest lifestyle, diet, and supplement steps, and Superpower says clinicians review decisions, edge cases, and changes that matter.¹
4. Retest. A second test of 50+ biomarkers later in the year tracks what changed.²

Superpower says results typically take about a week.² Members can upload past labs and sync wearables such as Oura, Whoop, and Apple Health.¹ Its concierge team says it responds within one business day.²

Superpower also runs a marketplace. Its FAQ says it offers supplements and prescription medicines, including compounded hormones and peptides, when clinically appropriate, and it notes that compounded drugs are not FDA-approved.² Keep that in mind if a protocol suggests products sold by the same company.

What's included

From Superpower's homepage and FAQ:¹²

Superpower's homepage groups tests into areas such as hormones and thyroid, heart and metabolic, energy (iron studies and ferritin), and a "DNA health" group that includes vitamin B12, folate, RBC folate, vitamin B6, and methylmalonic acid.¹ Its biomarker library notes, for the assays it describes, that results are interpreted by clinicians in context and are not a stand-alone diagnosis.⁴

Folate and vitamin B12 coverage

Superpower's biomarker library labels these as part of the baseline panel:⁴

How to read them sensibly:

• High folate is usually not a problem in itself. A high folate result often reflects recent fortified food or supplement intake and is not a diagnosis by itself.⁷⁶
• Low folate needs context. Folate and B12 deficiency can look alike, so a clinician checks both, along with a blood count, before treating.⁸⁹ See folic acid and vitamin B12.
• Ranges differ by lab. Use the reference range on your own report, not a number from the internet.⁶³ Our folate blood test guide explains serum versus RBC folate.

If you could become pregnant, the CDC advises 400 mcg of folic acid daily whatever your folate result shows.¹⁰ A normal folate number does not replace that advice; see folic acid before pregnancy.

Pricing and availability as listed (October 2026)

Superpower's homepage also shows a separate lab-location list that differs slightly from the FAQ list, so confirm your state at checkout.¹²

Pros and cons

From published facts, not our own use:

Is Superpower Health legit? What the company states

• Providers: Superpower says its providers include licensed physicians, nurse practitioners, and pharmacists.²
• Labs: Superpower describes many of its assays as FDA-cleared and performed in CLIA-certified, CAP-accredited laboratories, and labels others as lab-developed tests validated under CLIA.⁴
• Pharmacy: It says prescriptions are dispensed by U.S. partner pharmacies and that it is LegitScript certified.²
• Data: Superpower says data is encrypted, stored in HIPAA-compliant systems, never sold, and never shared with insurers, advertisers, or brokers, and that you can download or delete it.²¹

About member stories and survey numbers: Superpower's homepage cites a member survey (n=143) in which 60% said it found something a doctor missed.¹ That is a small, self-reported company survey, not a clinical study.

What to consider before broad screening

A Cochrane review of randomized trials covering about 252,000 adults found that offering general health checks had little or no effect on overall or cancer deaths, and noted that screening leads to more tests and treatments, which can cause harm as well as benefit.¹¹ Those trials did not study Superpower specifically. MedlinePlus adds that healthy people commonly have some results outside a reference range, and that an in-range result does not guarantee good health.³ The practical takeaway: plan who will review your results before you test.

How Superpower compares

• Function Health lists $365 per year for 160+ tests across two Quest visits, but did not list folate or serum B12 as included. See our Function Health review and the side-by-side Superpower vs Function Health.¹²¹³
• SiPhox Health uses an at-home upper-arm device and lets you test monthly, quarterly, or every 6 months; folate and B12 are in its upgraded Ultimate 360 panel. See our SiPhox review.¹⁴¹⁵

Questions to ask your clinician

• Which of these results would change what you recommend for me?
• If my folate or B12 is out of range, what follow-up do I need (for example a blood count)?⁷⁸
• Should I keep taking my supplements before the draw, and how should we read folate if I do?⁵
• Are any supplements or prescriptions suggested by the protocol safe with my current medicines?¹⁶

This article is for general education and is not medical advice. Doses and needs differ from person to person, so talk with your clinician or pharmacist about your situation. Read our editorial policy and medical disclaimer.