Folic Acid Awareness Week is January 6-12, 2013
Take our QUIZ
and test your
Folic Acid IQ
Member Login
Folic Acid Links
Alzheimer's Disease
"Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer’s Disease,”
Kruman I., et al, “Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer’s Disease,” The Journal of Neuroscience, Vol. 22, No. 5, Pages 1752-1762, March 2, 2002. Click To Visit Website
"Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer’s Disease,”
Seshadri, S., et al., “Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer’s Disease,” The New England Journal of Medicine, Vol. 346, No. 7, Pages 476-483, February 2002. Click To Visit Website
Folic Acid Possibly a Key Factor in Alzheimer’s Disease Prevention.
Click To Visit Website
Cancer
"Dietary Folate and Colorectal Cancer,”
La Vecchia, C.,et al., “Dietary Folate and Colorectal Cancer,” International Journal of Cancer, Vol. 102, Issue 5, Pages, 545-547, December 2002. Click To Visit Website
"Dietary Intake of folic Acid and Colorectal Cancer Risk in a Cohort of Women,”
Terry P., et al.,“Dietary Intake of folic Acid and Colorectal Cancer Risk in a Cohort of Women,” International Journal of Cancer,Vol.,97, Issue 6, Pages 864-867, February 20, 2002. Click To Visit Website
"Effect of folic acid supplementation of genomic DNA methylation in patients with colorectal adenoma,"
Pufulete M., et al., "Effect of folic acid supplementation of genomic DNA methylation in patients with colorectal adenoma," Gut, Vol. 54, pages 648-653, May 2005. Click To Visit Website
"Plasma Folate, Vitamin B6, Vitamin B12, Homocysteine, and Risk of Breast Cancer
Zhang, S.,et al., “Plasma Folate, Vitamin B6, Vitamin B12, Homocysteine, and Risk of Breast Cancer, Journal of the National Cancer Institute, Vol. 95, No. 5, Pages 373-380, March 5, 2003. Click To Visit Website
Action Medical Research
Click To Visit Website
“A Case-Control Study of Diet and Invasive Cervical Cancer”
Verreault, R., et al., “A Case-Control Study of Diet and Invasive Cervical Cancer”, International Journal of Cancer, Vol 43, Issue 6, Pages 1050-1054, 1989. Click To Visit Website
“Dietary Folate Intake and Breast Cancer Risk: Results from the Shanghai Breast Cancer Study, Cancer Research,"
Shrubsole, Martha J., et al., “Dietary Folate Intake and Breast Cancer Risk: Results from the Shanghai Breast Cancer Study, Cancer Research, Vol. 61, Pages 7136-7141, October 1, 2001. Click To Visit Website
“Dietary Folate Intake, Alcohol, and Risk of Breast Cancer in a Prospective Study of Postmenopausal Women, Epidemiology"
Sellers, Thomas A., et al., “Dietary Folate Intake, Alcohol, and Risk of Breast Cancer in a Prospective Study of Postmenopausal Women, Epidemiology, Vol 12, Pages 420-428, July 2001. Click To Visit Website
“Folate Deficiency and Cervical Dysplasia,”
Butterworth, CE Jr., et al., “Folate Deficiency and Cervical Dysplasia,” JAMA, Vol 267, Pages 528-533,No. 4, Pages 528-533, January 22, 1992. Click To Visit Website
“Folic Acid”, Web site of the American Cancer Society
Click To Visit Website
“Multivitamin Use, Folate, and Colon Cancer in Women in the nurses’ Health Study,”
Giovannucci E.,, et al, “Multivitamin Use, Folate, and Colon Cancer in Women in the nurses’ Health Study,” Annals of Internal Medicine, Vol. 129, Issue 7, Pages 517, 524, October 1998. Click To Visit Website
Centers for Disease Control and Prevention
Click To Visit Website
Cardiovascular Diseases
“Homocysteine, Diet, and Cardiovascular Diseases A Statement for Healthcare Professional From the Nutrition Committee, American Heart Association."
Malinow, M. et al.,“Homocysteine, Diet, and Cardiovascular Diseases A Statement for Healthcare Professional From the Nutrition Committee, American Heart Association." Click To Visit Website
Cleft Palate
"Periconceptional folate intake by supplement and food reduces the risk of nonsyndromic cleft lip with or without cleft palate"
van Rooij IALM., et al., "Periconceptional folate intake by supplement and food reduces the risk of nonsyndromic cleft lip with or without cleft palate", Preventive Medicine, Vol. 39, Issue 4, October 2004, Pages 689-694. Click To Visit Website
Down's Syndrome
“Frequency of Down’s syndrome and neural-tube defects in the same family”
Barkai G., et al., “Frequency of Down’s syndrome and neural-tube defects in the same family”, The Lancet, 2003, Vol. 361, Issue 9366, Page 1331-35. Click To Visit Website
Folic Acid Information in Other Languages
Preventing Neural Tube Defects for Couples at Increased Risk
Click To Visit Website
Russian: How Diet Can Prevent Birth Defects
(Australian folic acid recommendations) — available in Arabic, Chinese, Croatian, English, Italian, Khmer/Cambodian, Korean, Portuguese, Russian, Serbian, Spanish, Thai, Turkish, and Vietnamese Click To Visit Website
Folic Acid Materials Available
Centers for Disease Control and Prevention
Click To Visit Website
Florida Folic Acid Council
Click To Visit Website
March of Dimes
Click To Visit Website
National Alliance for Hispanic Health Telephone Hotline and Helpline
Click To Visit Website
North Carolina Folic Acid Council
Click To Visit Website
Spina Bifida Association
Click To Visit Website
Tennessee Folic Acid Council
Click To Visit Website
The Pregnancy Foresight Project
The Pregnancy Foresight Project has translated and made available on their Web site information about folic acid and preconception brochures in English, Spanish, Russian, Ukrainian, Vietnamese, Korean, Chinese and Somali Click To Visit Website
Fortification
"Decline in the Prevalence of Spina Bifida and Anencephaly by Race/Ethnicity: 1998-2002,"
Williams, Laura, et al., "Decline in the Prevalence of Spina Bifida and Anencephaly by Race/Ethnicity: 1998-2002," Pediatrics, Vol. 116, No. 3, September 2005, pp. 580-586. Click To Visit Website
"Do racial and ethnic differences in serum folate values exist after food fortification with folic acid?"
Lawence, Jean M., et al., "Do racial and ethnic differences in serum folate values exist after food fortification with folic acid?", American Journal of Obstetrics and Gynecology, Vol. 194, Issue 2, pp. 520-526. Click To Visit Website
"Reevaluating the Benefits of Folic Acid Fortification in the United States: Economic Analysis, Regulation, and Public Health,"
Grosse S., et al, "Reevaluating the Benefits of Folic Acid Fortification in the United States: Economic Analysis, Regulation, and Public Health," The American Journal of Public Health, Vol 905, No. 11, Pages 1917-1922, November 2005. Click To Visit Website
“Folic Acid Food Fortification is Associated with a decline in Neuroblastoma,”
French, A., et al., “Folic Acid Food Fortification is Associated with a decline in Neuroblastoma,” Clinical Pharmacology & Therapeutics, Vol. 74, Number 3, September 2003. Click To Visit Website
Spina Bifida and Anencephaly Before and After Folic Acid Mandate
United States, 1995- 1996 and 1999-2000.”CDC Morbidity and Mortality Weekly Review, May 7, 2004/53(17);362-365. Click To Visit Website
General Links
"Determining bioavailability of food folates in a controlled intervention study,"
Hannon-Fletcher, Mary P., et al, "Determining bioavailability of food folates in a controlled intervention study," American Journal of Clinical Nutrition, Vol. 80, No.4, 911-918, October 2004. Click To Visit Website
"Exposure to Fumonisins and the Occurrence of Neural Tube Defects along the Texas-Mexico Border,"
Missmer, Stacey A., et al., "Exposure to Fumonisins and the Occurrence of Neural Tube Defects along the Texas-Mexico Border," Environmental Health Perspectives, Vol. 114, No.2, pp. 237-241, February 2006. Click To Visit Website
"Greater maternal weight and the ongoing risk of neural tube defects after folic acid flour fortification,"
Ray, J.G., et al., "Greater maternal weight and the ongoing risk of neural tube defects after folic acid flour fortification," Obstet Gynecol 2005: 105: 261-5. Click To Visit Website
"International retrospective cohort study of neural tube defects in relation to folic acid recommendations: Are the recommendations working?"
Botto, Lorenzo, D., et al., "International retrospective cohort study of neural tube defects in relation to folic acid recommendations: Are the recommendations working?" British Medical Journal, February 2005. Click To Visit Website
"The primary prevention of birth defects: Multivitamins or folic acid?
Czeizel AE. "The primary prevention of birth defects: Multivitamins or folic acid?". Int J Med Sci 2004; 1:50-61. Click To Visit Website
"Trends and Predictors of Folic Acid Awareness and Periconceptional use in Pregnant Women,"
Lolkje, T.W. De Jong-van den Berg, et al., "Trends and Predictors of Folic Acid Awareness and Periconceptional use in Pregnant Women," The American Journal of Obstetrics and Gynecology, Vol. 192, Issue 1, pp 121-128, January 2005. Click To Visit Website
Grand Rounds
Homocysteine
"Homocysteine and Cognitive Performance in the Framingham Offspring Study: Age is Important,"
Elias, Merrill F. et al., "Homocysteine and Cognitive Performance in the Framingham Offspring Study: Age is Important," American Journal of Epidemiology, Vol. 162, No. 7, pp. 644-653. Click To Visit Website
"Homocysteine, Vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus Study,"
Mooijaart, Simon P., et al., "Homocysteine, Vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus Study," American Journal of Clinical Nutrition, Vol. 82, No. 4, pp. 866-871, October 2005. Click To Visit Website
"Mapping the theories of preeclampsia: the role of homocysteine,"
Mignini L.E., et al., "Mapping the theories of preeclampsia: the role of homocysteine," Obstet Gynecol 2005; 105: 411-25. Click To Visit Website
Hypertension
"Folate Intake and the Risk of Incident Hypertension Among US Women,"
Forman, John P., et al, "Folate Intake and the Risk of Incident Hypertension Among US Women," JAMA, Vol. 293, No. 3, January 19, 2005. Click To Visit Website
Leukemia
The Leukaemia Research Fund, News Release, April 24, 2003.
Click To Visit Website
Men's Reproductive Health
Adequate Folic Acid in Diet May Be Important for Both Men and Women of Reproductive Age, Suggests UC Berkeley Study.
Click To Visit Website
Stroke
“Dietary Intake of Folate and Risk of Stroke in US Men and Women, NHANES I Epidemiologic Follow-Up Study,”
Bazzano L., et al., “Dietary Intake of Folate and Risk of Stroke in US Men and Women, NHANES I Epidemiologic Follow-Up Study,” Stroke; Vol. 33, Pages 1183-1189, 2002. Click To Visit Website
“Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial,”
Wong, W., et al., “Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial,” Fertility and Sterility, Vol. 77, No.3, March 2002. Click To Visit Website
Twinning
"Effects of folic acid fortification on twin gestation rates,"
Signiore, C., et al., "Effects of folic acid fortification on twin gestation rates," Obstet Gynecol 2005: 105: 757-762. Click To Visit Website
"Impact of misclassification of in vitro fertilization in studies of folic acid and twinning: modelling using populated based Swedish vital records,
Berry, RJ, et al., "Impact of misclassification of in vitro fertilization in studies of folic acid and twinning: modelling using populated based Swedish vital records," British Medical Journal, February 2005 Click To Visit Website